12/5/2023 0 Comments Sonic the hedgehog 1 loopFibroblast growth factor (FGF) can replace the ridge 3,4 and, because Fgf4RNA is localized to the mouse posterior ridge 5, we proposed that FGF4 is the endogenous ridge signal 3. LIMB development depends on signals from the apical ectodermal ridge and underlying mesenchyme 1,2.
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